1. aSee:http://www.ich.org/.
2. bFor details, see: Guideline on the specification limits for residues of metal catalysts or metal reagents, EMEA/CHMP/SWP/4446/2000.
3. Efficient Synthesis of Losartan, A Nonpeptide Angiotensin II Receptor Antagonist
4. bGiguere, P.; Iera, S.; Bernatchez, M.; Barreca, G.; Castaldi, G.; Cannata, V.;Process for preparation of biphenyl derivatives.PCT Int. Appl., WO 199640684, CAN 126131464, 1996.
5. Practical Asymmetric Synthesis of a Potent Cathepsin K Inhibitor. Efficient Palladium Removal Following Suzuki Coupling