Efficient Large-Scale Process for Tecovirimat via Reactive Distillation for the Preparation of Cycloheptatriene-Reference-Cited by-同舟云学术

Efficient Large-Scale Process for Tecovirimat via Reactive Distillation for the Preparation of Cycloheptatriene

Published:2023-09-15 Issue:11 Volume:27 Page:1984-1991
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Bonku Emmanuel Mintah¹²^ORCID,Qin Hongjian¹²³,Odilov Abdullajon¹²^ORCID,Yang Feipu¹^ORCID,Xing Xinglong⁴,Wang Xukun⁴,Guma Samuel Desta¹²,Shen Jingshan¹²^ORCID

Affiliation:

1. State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, P. R. China

2. University of Chinese Academy of Sciences, No. 19A Yuquan Road, Beijing 100049, P. R. China

3. Key Laboratory of Plant Resources and Chemistry in Arid Regions, Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, South Beijing Road 40-1, Urumqi, Xinjiang 830011, P. R. China

4. Vigonvita Life Science Co., Ltd., 108 Yuxin Road, Suzhou Industrial Park, Suzhou, Jiangsu 215123, P. R. China

Funder

University of Chinese Academy of Sciences

Science and Technology Commission of Shanghai Municipality

Chinese Academy of Sciences

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.3c00151

Reference41 articles.

1. Emergence of Monkeypox as the Most Important Orthopoxvirus Infection in Humans

2. 2018, https://www.fda.gov/Drugs/GuidanceComplianceRegulatoryInformation (accessed on July 13th, 2018).

3. 2021, Available online: https://www.ema.europa.eu/en/medicines/human/EPAR/tecovirimat-siga (accessed on July 11th, 2022).

4. Tecovirimat, SIGA. European Medicines Agency. 2022, https://www.ema.europa.eu/en/medicines/human/EPAR/tecovirimat-siga (accessed on January 28th, 2022).

5. aJordan, R.; Bailey, T. R.; Rippin, S. R.; Dai, D. Compounds, Compositions and Methods for Treatment and Prevention of Orthopoxvirus Infections and Associated Diseases. U.S. Patent 8,530,509 B2, Sep 10, 2013.