One-Step Synthesis of 2-Fluoroadenine Using Hydrogen Fluoride Pyridine in a Continuous Flow Operation-Reference-Cited by-同舟云学术

One-Step Synthesis of 2-Fluoroadenine Using Hydrogen Fluoride Pyridine in a Continuous Flow Operation

Published:2019-06-26 Issue:8 Volume:23 Page:1522-1528
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Salehi Marzijarani Nastaran¹^ORCID,Snead David R.¹,McMullen Jonathan P.¹^ORCID,Lévesque François¹^ORCID,Weisel Mark¹,Varsolona Richard J.¹,Lam Yu-hong²,Liu Zhijian¹^ORCID,Naber John R.¹^ORCID

Affiliation:

1. Process Research & Development, MRL, Merck & Co. Inc., P.O. Box 2000, Rahway, New Jersey 07065, United States

2. Modeling and Informatics, Merck & Co. Inc., P.O. Box 2000, Rahway, New Jersey 07065, United States

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.9b00178

Reference34 articles.

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2. Synthesis and applications of fluorinated nucleoside analogues

3. Recent advances in the selective formation of the carbon-fluorine bond

4. Nucleic acid related compounds. 34. Non-aqueous diazotization with tert-butyl nitrite. Introduction of fluorine, chlorine, and bromine at C-2 of purine nucleosides

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