A Tandem Ring Closure and Nitrobenzene Reduction with Sulfide Provides an Improved Route to an Important Intermediate for the Anti-Tuberculosis Drug Candidate Sutezolid-Reference-Cited by-同舟云学术

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A Tandem Ring Closure and Nitrobenzene Reduction with Sulfide Provides an Improved Route to an Important Intermediate for the Anti-Tuberculosis Drug Candidate Sutezolid

Published:2024-03-27 Issue:4 Volume:28 Page:1195-1204
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Kalmode Hanuman P.¹^ORCID,Ravikumar Ongolu¹,Paymode Dinesh J.¹^ORCID,Bachert John¹,Burns Justina M.¹,Stringham Rodger W.¹,Aleshire Sarah L.¹^ORCID,Nelson Ryan C.¹^ORCID

Affiliation:

1. Medicines for All Institute, 737 N Fifth St., Box 980100, Richmond, Virginia 23298, United States

Funder

Grand Challenges in Global Health

Bill and Melinda Gates Foundation

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.4c00014

Reference26 articles.

1. Tuberculosis https://www.who.int/news-room/questions-and-answers/item/tuberculosis (accessed 2023 −09 −05).

2. Tuberculosis (TB) https://www.who.int/news-room/fact-sheets/detail/tuberculosis (accessed 2023 −09 −05).

3. CDCTB. Tuberculosis (TB) - Drug-Resistant TB https://www.cdc.gov/tb/topic/drtb/default.htm (accessed 2023 −09 −05).

4. From Drugs to Regimens: Transforming TB Drug Development https://www.tballiance.org/content/drugs-regimens-transforming-tb-drug-development (accessed 2024 −01 −31).

5. Diastereoselectivity is in the Details: Minor Changes Yield Major Improvements to the Synthesis of Bedaquiline**

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