Population Balance Modeling To Predict Particle Size Distribution upon Scale-Up of a Combined Antisolvent and Cooling Crystallization of an Active Pharmaceutical Ingredient-Reference-Cited by-同舟云学术

Population Balance Modeling To Predict Particle Size Distribution upon Scale-Up of a Combined Antisolvent and Cooling Crystallization of an Active Pharmaceutical Ingredient

Published:2019-11-15 Issue:12 Volume:23 Page:2666-2677
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Rosenbaum Tamar^ORCID,Tan Li,Dummeldinger Michael,Mitchell Niall¹,Engstrom Joshua^ORCID

Affiliation:

1. Process Systems Enterprise (PSE) Ltd., 26-28 Hammersmith Grove, London W6 7HA, U.K.

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.9b00348

Reference35 articles.

1. Recent Advances in Crystallization control

2. From form to function: Crystallization of active pharmaceutical ingredients

3. The Impact of Direct Nucleation Control on Crystal Size Distribution in Pharmaceutical Crystallization Processes

4. Control of the Particle Properties of a Drug Substance by Crystallization Engineering and the Effect on Drug Product Formulation

5. Model-Based Optimal Strategies for Controlling Particle Size in Antisolvent Crystallization Operations

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