Practical Synthesis of (3aR, 9bR)-8-Fluoro-7-(perfluoropropan-2-yl)-9b-(phenylsulfonyl)-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole: An Advanced Intermediate to Access the RORγt Inverse Agonist BMT-362265-Reference-Cited by-同舟云学术

Practical Synthesis of (3aR, 9bR)-8-Fluoro-7-(perfluoropropan-2-yl)-9b-(phenylsulfonyl)-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole: An Advanced Intermediate to Access the RORγt Inverse Agonist BMT-362265

Published:2021-03-16 Issue:4 Volume:25 Page:1001-1014
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Karmakar Ananta¹^ORCID,Nimje Roshan Y.¹,Silamkoti Arundutt¹,Pitchai Manivel¹,Basha Mushkin¹,Singarayer Christuraj¹,Ramasamy Duraisamy¹,Babu G. T. Venkatesh¹,Samikannu Ramesh¹,Subramaniam Srinath¹,Anjanappa Prakash¹,Vetrichelvan Muthalagu¹^ORCID,Kumar Hemantha¹,Dikundwar Amol G.²,Gupta Anuradha¹^ORCID,Gupta Arun Kumar¹,Rampulla Richard³,Dhar T. G. Murali³^ORCID,Mathur Arvind³

Affiliation:

1. Department of Discovery Synthesis, Biocon Bristol Myers Squibb R&D Centre, Syngene International Ltd., Biocon Park, Plot No. 2 & 3, Bommasandra-Jigani Road, Bangalore 560099, India

2. Analytical Research & Development, Biocon Bristol Myers Squibb R&D Centre, Syngene International Ltd., Biocon Park, Plot No. 2 & 3, Bommasandra-Jigani Road, Bangalore 560099, India

3. Small Molecule Drug Discovery, Bristol Myers Squibb Research and Development, P.O. Box 5400, Princeton, New Jersey 08543-4000, United States

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.1c00019

Reference39 articles.

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4. The IL-17 Family Cytokines in Immunity and Disease

5. The psoriasis drugs market

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