A Scalable Route for the Regio- and Enantioselective Preparation of a Tetrazole Prodrug: Application to the Multi-Gram-Scale Synthesis of a PCSK9 Inhibitor-Reference-Cited by-同舟云学术

A Scalable Route for the Regio- and Enantioselective Preparation of a Tetrazole Prodrug: Application to the Multi-Gram-Scale Synthesis of a PCSK9 Inhibitor

Published:2017-11-16 Issue:12 Volume:21 Page:1990-2000
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Akin Anne,Barrila Mark T.,Brandt Thomas A.,Dechert-Schmitt Anne-Marie R.,Dube Pascal¹,Ford David D.¹,Kamlet Adam S.,Limberakis Chris,Pearsall Andrew¹,Piotrowski David W.^ORCID,Quinn Brian¹,Rothstein Sarah¹,Salan Jerry¹,Wei Liuqing,Xiao Jun

Affiliation:

1. Nalas Engineering Services, Inc., 85 Westbrook Road, Centerbrook, Connecticut 06409, United States

Funder

Pfizer, Inc.

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.7b00304

Reference24 articles.

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