Safe and Efficient Decarboxylation Process: A Practical Synthetic Route to 4-Chlorobenzo[b]thiophene-Reference-Cited by-同舟云学术

Safe and Efficient Decarboxylation Process: A Practical Synthetic Route to 4-Chlorobenzo[b]thiophene

Published:2015-12-21 Issue:1 Volume:20 Page:86-89
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Miyake Masahiro¹,Shimizu Masamichi¹,Tsuji Koichi¹,Ikeda Keiichi¹

Affiliation:

1. Bulk Pharmaceutical Chemicals Department, Second Tokushima Factory, Production Headquarters, Otsuka Pharmaceutical Co., Ltd., 224-18, Hiraishi Ebisuno, Kawauchi-cho, Tokushima 771-0182, Japan

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.5b00340

Reference25 articles.

1. Efficacy and Safety of Brexpiprazole for the Treatment of Acute Schizophrenia: A 6-Week Randomized, Double-Blind, Placebo-Controlled Trial

2. Brexpiprazole II: Antipsychotic-Like and Procognitive Effects of a Novel Serotonin-Dopamine Activity Modulator

3. aHansen, M. M.; He, J.X.; Honigschmidt, N. A.; Koch, D. J.; Kohn, T. J.; Rocco, V. P.; Spinazze, P. G.; Takeuchi, K.Indole Derivatives for the Treatment of Depression and Anxiety. US2004006229(A1), Jan 8, 2014.

4. bShinhama, K.; Utsumi, N.; Sota, M.; Fujieda, S.; Ogasawara, S.Method for Producing Benzo[b]thiophene Compound. WO2013015456, Jan 31, 2013.

5. An improved synthesis of substituted benzo[b]thiophenes using microwave irradiation

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