Development of a Green and Sustainable Manufacturing Process for Gefapixant Citrate (MK-7264) Part 1: Introduction and Process Overview-Reference-Cited by-同舟云学术

Development of a Green and Sustainable Manufacturing Process for Gefapixant Citrate (MK-7264) Part 1: Introduction and Process Overview

Published:2020-10-16 Issue:11 Volume:24 Page:2445-2452
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Ren Hong¹^ORCID,Maloney Kevin M.¹^ORCID,Basu Kallol¹^ORCID,Di Maso Michael J.¹^ORCID,Humphrey Guy R.¹^ORCID,Peng Feng¹^ORCID,Desmond Richard¹,Otte Douglas A. L.¹^ORCID,Alwedi Embarek¹^ORCID,Liu Wenjun¹,Zhang Si-Wei¹^ORCID,Song Siqing¹,Arvary Rebecca A.¹,Zompa Michael A.¹,Lehnherr Dan¹^ORCID,Martin Gary E.¹^ORCID,Chang Hsieh Yao D.¹,Mohan Anne E.¹,Guzman Francisco J.¹,Jellett Lisa¹,Lee Alfred Y.¹^ORCID,Spencer Glenn¹,Fisher Elizabeth S.¹,Naber John R.¹^ORCID,Gao Hong¹,Lohani Sachin¹,Ruck Rebecca T.¹^ORCID,Campeau Louis-Charles¹^ORCID

Affiliation:

1. Department of Process Research and Development, Merck & Co., Inc., Rahway, New Jersey 07065, United States

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.0c00248

Reference33 articles.

1. The global epidemiology of chronic cough in adults: a systematic review and meta-analysis

2. Update on novel purinergic P2X3 and P2X2/3 receptor antagonists and their potential therapeutic applications

3. The digitization of organic synthesis

4. bMerck processes have received the EPA/ACS Green Chemistry Challenge Greener Synthetic Pathways award in 2005, 2010, 2017, 2018 and 2019. See: Green Chemistry Challenge Winners, https://www.epa.gov/greenchemistry/green-chemistry-challenge-winners (retrieved March 26, 2020).

Cited by 27 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Tandem Synthesis of Benzylidenemalononitrile Derivatives in/on Water under Visible Light;ChemCatChem;2024-08-20

2. Development of a Green and Sustainable Manufacturing Process for a Key Intermediate to Nemtabrutinib (MK-1026): Sequential Deprotonation–Lithiation as a Batch–Flow Process;Organic Process Research & Development;2024-05-09

3. Synthetic Approaches to the New Drugs Approved During 2022;Journal of Medicinal Chemistry;2024-03-15

4. Challenges with retention and recovery of impurities containing acidic moieties during analytical UHPLC method development and validation for gefapixant freebase;Journal of Pharmaceutical and Biomedical Analysis;2024-01

5. The Airfoil Design for Small-Scale Wind Turbines in Maximizing Renewable Wind Energy;Lecture Notes in Electrical Engineering;2024