Oligonucleotide Purification by Ion Exchange Chromatography: A Step-by-Step Guide to Process Understanding, Modeling, and Simulation-Reference-Cited by-同舟云学术

Oligonucleotide Purification by Ion Exchange Chromatography: A Step-by-Step Guide to Process Understanding, Modeling, and Simulation

Published:2024-04-11 Issue:7 Volume:28 Page:2569-2589
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Kobl Kilian¹^ORCID,Nicoud Lucrèce¹,Nicoud Edouard¹,Watson Anna²,Andrews John²,Wilkinson Edward A.²^ORCID,Shahid Muhid²,McKay Christopher³^ORCID,Andrews Benjamin I.³^ORCID,Omer Batool Ahmed³,Narducci Olga³,Masson Edward³,Davies Suzanne H.³,Vandermeersch Tobias⁴

Affiliation:

1. Ypso-Facto, 19 Avenue Foch, 54000 Nancy, France

2. AstraZeneca, Chemical Development, Pharmaceutical Technology & Development, Operations, AstraZeneca, Macclesfield SK10 2NA, U.K.

3. Chemical Development, GSK, Gunnels Wood Road, Stevenage SG1 2NY, U.K.

4. Johnson and Johnson, Turnhoutseweg 30, 2340 Beerse, Belgium

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.4c00013

Reference34 articles.

1. Biopharma PEG. https://www.biochempeg.com/article/124.html. 2020 (accessed 19 Sep 2023).

2. Oligonucleotides: Current Trends and Innovative Applications in the Synthesis, Characterization, and Purification

3. Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing

4. Chromatographic Processes

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