Fit-for-Purpose Synthesis of an Aza-Cryptophycin Analogue as the Payload for an Antibody–Drug Conjugate
Author:
Affiliation:
1. ADC Conjugation Development, Sanofi, 13 Quai Jules Guesde, 94403 Vitry-sur-Seine Cedex, France
2. Early Development Chemistry, Sanofi, 13 Quai Jules Guesde, 94403 Vitry-sur-Seine Cedex, France
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.2c00080
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4. aMoore, R. E.; Tius, M. A.; Barrow, R. A.; Liang, J.; Corbett, T. H.; Valeriote, F. A.; Hemscheidt, T. K. WO 9640184 A1, 1996.
5. In vitro pharmacology of cryptophycin 52 (LY355703) in human tumor cell lines
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