Side-Chain Unprotected Fmoc-Arg/His/Tyr-OH Couplings and Their Application in Solid-Phase Peptide Synthesis through a Minimal-Protection/Green Chemistry Strategy-Reference-Cited by-同舟云学术

Side-Chain Unprotected Fmoc-Arg/His/Tyr-OH Couplings and Their Application in Solid-Phase Peptide Synthesis through a Minimal-Protection/Green Chemistry Strategy

Published:2022-05-04 Issue:5 Volume:26 Page:1520-1530
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Yang Yi¹^ORCID,Hansen Lena¹,Ryberg Per¹

Affiliation:

1. Chemical Development, Global Pharmaceutical R&D, Ferring Pharmaceuticals A/S, Amager Strandvej 405, 2770 Kastrup, Denmark

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.2c00083

Reference15 articles.

1. Amino Acid-Protecting Groups

2. The 2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl group (Pbf) as arginine side chain protectant

3. Acylation of unprotected amino acids using ultrasound

4. Peptide coupling of unprotected amino acids through in situ p-nitrophenyl ester formation

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