Process Intensification and Integration Studies for the Generation of a Key Aminoimidazole Intermediate in the Synthesis of Lanabecestat-Reference-Cited by-同舟云学术

Process Intensification and Integration Studies for the Generation of a Key Aminoimidazole Intermediate in the Synthesis of Lanabecestat

Published:2018-04-26 Issue:5 Volume:22 Page:633-640
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Znidar Desiree¹²,Cantillo David¹²,Inglesby Phillip³,Boyd Alistair³,Kappe C. Oliver¹²^ORCID

Affiliation:

1. Center for Continuous Flow Synthesis and Processing (CC FLOW), Research Center Pharmaceutical Engineering GmbH (RCPE), Inffeldgasse 13, 8010 Graz, Austria

2. Institute of Chemistry, University of Graz, NAWI Graz, Heinrichstrasse 28, 8010 Graz, Austria

3. AstraZeneca, Silk Road Business Park, Macclesfield SK10 2NA, United Kingdom

Funder

Bundesministerium f?r Wissenschaft, Forschung und Wirtschaft

Bundesministerium f?r Verkehr, Innovation und Technologie

Steirische Wirtschaftsf?rderungsgesellschaft

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.8b00089

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