Establishment and Development of Organolithium-Mediated Continuous Flow Process for Intermediate of Canagliflozin-Reference-Cited by-同舟云学术

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Establishment and Development of Organolithium-Mediated Continuous Flow Process for Intermediate of Canagliflozin

Published:2024-01-25 Issue: Volume: Page:
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Yano Gemba¹^ORCID,Hyakumura Mai¹,Nakano Kimihiro²,Yasukouchi Hiroaki¹^ORCID,Kawachi Hideo¹,Funabashi Makoto¹,Ohishi Takahiro³,Ogawa Yu³,Nishiyama Akira¹

Affiliation:

1. Pharma Research Group, Pharma & Supplemental Nutrition Solutions Vehicle, Kaneka Corporation, 1-8, Miyamae-cho, Takasago-cho, Takasago, Hyogo 676-8688, Japan

2. Osaka Synthetic Chemical Laboratories, Inc., 1-1-2, Nishinomiyahama, Nishinomiya, Hyogo 662-0934, Japan

3. Engineering Research Laboratories, Kaneka Corporation, 1-8, Miyamae-cho, Takasago-cho, Takasago, Hyogo 676-8688, Japan

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.3c00385

Reference22 articles.

1. Discovery of Canagliflozin, a Novel C-Glucoside with Thiophene Ring, as Sodium-Dependent Glucose Cotransporter 2 Inhibitor for the Treatment of Type 2 Diabetes Mellitus

2. Discovery of Dapagliflozin: A Potent, Selective Renal Sodium-Dependent Glucose Cotransporter 2 (SGLT2) Inhibitor for the Treatment of Type 2 Diabetes

3. Canagliflozin: First Global Approval

4. Ipragliflozin: First Global Approval

5. Tofogliflozin: First Global Approval

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