Process Development of the HCV NS5B Site D Inhibitor MK-8876-Reference-Cited by-同舟云学术

Process Development of the HCV NS5B Site D Inhibitor MK-8876

Published:2016-07-01 Issue:7 Volume:20 Page:1227-1238
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Williams Michael J.¹,Chen Qinghao¹,Codan Lorenzo²,Dermenjian Renee K.¹,Dreher Spencer¹,Gibson Andrew W.³,He Xianliang⁴,Jin Yan¹,Keen Stephen P.³,Lee Alfred Y.¹,Lieberman David R.³,Lin Wei⁴,Liu Guiquan⁴,McLaughlin Mark¹,Reibarkh Mikhail¹,Scott Jeremy P.³,Strickfuss Sophie³,Tan Lushi¹,Varsolona Richard J.¹,Wen Feng⁴

Affiliation:

1. Department of Process Research and Development, Merck Research Laboratories, Rahway, New Jersey 07065, United States

2. Werthenstein BioPharma GmbH (MSD Switzerland), Industrie Nord 1, CH-6105 Schachen, Switzerland

3. Department of Process Chemistry, Merck Sharp & Dohme Ltd., Hertford Road, Hoddesdon, Hertfordshire EN11 9BU, United Kingdom

4. WuXi AppTec Co., Ltd., No. 1 Building, #288 FuTe ZhongLu, WaiGaoQiao Free Trade Zone, Shanghai 200131, China

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.5b00405

Reference24 articles.

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5. bMcComas, C. C.; Liverton, N. J.; Habermann, J.; Koch, U.; Narjes, F.; Li, P.; Peng, X.; Soll, R.; Wu, H.; Palani, A.; He, S.; Dai, X.; Liu, H.; Lai, Z.; London, C.; Xiao, D.; Zorn, N.; Nargund, R.Preparation of pyridooxazinoindole derivatives and analogs for use as antiviral agents. WO 2013033971 A1 20130314, 2013.

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