Development of a Practical, Biocatalytic Synthesis of tert-Butyl (R)-3-Hydroxyl-5-hexenoate: A Key Intermediate to the Statin Side Chain-Reference-Cited by-同舟云学术

Development of a Practical, Biocatalytic Synthesis of tert-Butyl (R)-3-Hydroxyl-5-hexenoate: A Key Intermediate to the Statin Side Chain

Published:2020-08-21 Issue:9 Volume:24 Page:1700-1706
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Hu Chen¹²,Liu Minjie¹²,Yue Xiaoping³,Huang Zedu¹²^ORCID,Chen Fener¹²^ORCID

Affiliation:

1. Engineering Center of Catalysis and Synthesis for Chiral Molecules, Department of Chemistry, Fudan University, 220 Handan Road, Shanghai 200433, P. R. China

2. Shanghai Engineering Research Center of Industrial Asymmetric Catalysis of Chiral Drugs, 220 Handan Road, Shanghai 200433, P. R. China

3. West China School of Pharmacy, Sichuan University, Chengdu 610041, P. R. China

Funder

Science and Technology Commission of Shanghai Municipality

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.0c00320

Reference38 articles.

1. Statin: New life for an old drug

2. The power of statins: Aggressive lipid lowering

3. The Discovery of Statins

4. Historic Overview and Recent Advances in the Synthesis of Super-statins

5. Biocatalyzed Synthesis of Statins: A Sustainable Strategy for the Preparation of Valuable Drugs

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