1. Process Chemistry and Development, Takeda Pharmaceuticals International Company, Boston, 40 Landsdowne, Cambridge, Massachusetts 02139, United States
2. EPSRC Future CMAC Manufacturing Research Hub, Institute of Pharmacy & Biomedical Sciences, Technology and Innovation Centre, University of Strathclyde, Glasgow G1 1RD, U.K.
3. EPSRC Future CMAC Manufacturing Research Hub, Department of Chemical and Biological Engineering, University of Sheffield, Sheffield S1 3JD, U.K.