1. Chemical Computing Group, 1010 Sherbrooke Street West, Suite 910, Montreal, Quebec H3A 2R7, Lead Discovery Center, Room 2605, Novartis Institutes for BioMedical Research Inc., 100 Technology Square, Cambridge Massachusetts 02139, and Department of Pharmacology & Toxicology, College of Pharmacy, University of Arizona, 1703 East Mabel, P.O. Box 210207, Tucson, Arizona 85721