Synthetic and Biosynthetic Studies on FR900482 and Mitomycin C: An Efficient and Stereoselective Hydroxymethylation of an Advanced Benzazocane Intermediate-Reference-Cited by-同舟云学术

Synthetic and Biosynthetic Studies on FR900482 and Mitomycin C: An Efficient and Stereoselective Hydroxymethylation of an Advanced Benzazocane Intermediate

Published:2007-11-30 Issue:26 Volume:9 Page:5341-5344
ISSN:1523-7060
Container-title:Organic Letters
language:en
Short-container-title:Org. Lett.

Author:

Namiki Hidenori¹,Chamberland Stephen¹,Gubler Daniel A.¹,Williams Robert M.¹

Affiliation:

1. Department of Chemistry, Colorado State University, Fort Collins, Colorado 80523-1872, and University of Colorado Cancer Center, Aurora, Colorado 80045

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ol701960v

Reference21 articles.

1. Mechanisms of in Situ Activation for DNA-Targeting Antitumor Agents

2. DNA Cross-Linking Agents as Antitumor Drugs

3. Differential Effects of FR900482 and FK317 on Apoptosis, IL-2 Gene Expression, and Induction of Vascular Leak Syndrome

4. FR900482 class of anti-tumor drugs cross-links oncoprotein HMG I/Y to DNA in vivo

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