Complete Regioselective Addition of Grignard Reagents to Pyrazine N-Oxides, Toward an Efficient Enantioselective Synthesis of Substituted Piperazines-Reference-Cited by-同舟云学术

Complete Regioselective Addition of Grignard Reagents to Pyrazine N-Oxides, Toward an Efficient Enantioselective Synthesis of Substituted Piperazines

Published:2009-12-11 Issue:2 Volume:12 Page:284-286
ISSN:1523-7060
Container-title:Organic Letters
language:en
Short-container-title:Org. Lett.

Author:

Andersson Hans¹,Banchelin Thomas Sainte-Luce¹,Das Sajal¹,Gustafsson Magnus¹,Olsson Roger¹,Almqvist Fredrik¹

Affiliation:

1. Department of Chemistry, Umeå University, SE-90187 Umeå, Sweden, ACADIA Pharmaceuticals AB, Medeon Science Park S-20512, Malmö, Sweden, and Department of Chemistry, University of Gothenburg, Kemivägen 10, 41296 Gothenburg

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ol902619h

Reference18 articles.

1. Synthesis of 2-Substituted Pyridines via a Regiospecific Alkylation, Alkynylation, and Arylation of Pyridine N-Oxides

2. Regioselective addition of Grignard reagents to 1-acylpyridinium salts. A convenient method for the synthesis of 4-alkyl(aryl)pyridines

3. Practical and Highly Regio- and Stereoselective Synthesis of 2-Substituted Dihydropyridines and Piperidines: Application to the Synthesis of (−)-Coniine

4. The Regio- and Stereoselective Synthesis oftrans-2,3-DihydropyridineN-oxides and Piperidines

5. Complexation Promoted Additions to N-Benzoyliminopyridinium Ylides. A Novel and Highly Regioselective Approach to Polysubstituted Piperidines

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