Effect of enzyme and ligand protonation on the binding of folates to recombinant human dihydrofolate reductase: implications for the evolution of eukaryotic enzyme efficiency-Reference-Cited by-同舟云学术

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Effect of enzyme and ligand protonation on the binding of folates to recombinant human dihydrofolate reductase: implications for the evolution of eukaryotic enzyme efficiency

Published:1992-04 Issue:14 Volume:31 Page:3709-3715
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Appleman James R.,Tsay Jiu Tsair,Freisheim James H.,Blakley Raymond L.

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/bi00129a021

Cited by 14 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Evolutionary Effects on Bound Substrate pKa in Dihydrofolate Reductase;Journal of the American Chemical Society;2018-11-06

2. Differentiation of Folate-Receptor-Positive and -Negative Cells Using a Substrate-Mimicking Fluorescent Probe;Chemistry - A European Journal;2017-10-06

3. Inhibitory properties and X-ray crystallographic study of the binding of AR-101, AR-102 and iclaprim in ternary complexes with NADPH and dihydrofolate reductase fromStaphylococcus aureus;Acta Crystallographica Section D Biological Crystallography;2009-07-10

4. Mammalian Dihydrofolate Reductase;xPharm: The Comprehensive Pharmacology Reference;2007

5. Eukaryotic Dihydrofolate Reductase;Advances in Enzymology - and Related Areas of Molecular Biology;2006-11-22

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