Efficient Synthesis of 8-Oxa-3-aza-bicyclo[3.2.1]octane Hydrochloride
Author:
Affiliation:
1. Chemical Development, Wyeth Research, 401 North Middletown Road, Pearl River, New York 10965, U.S.A.
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/op9002642
Reference21 articles.
1. Early Process Development: The Wyeth Approach
2. Aminoalcohols Containing the 8-Oxa-3-azabicyclo [3.2.1]octane Ring System and Their Benzoates
3. 1. The conversion of sucrose into furan compounds. Part II. Some 2 : 5-disubstituted tetrahydrofurans and their products of ring scission
4. Screening was performed using an Endeavor Catalyst Screening System from Biotage/Argonaut.
5. 13C NMR supported the 95/5 ratio of isomers determined by GC. See theExperimental Sectionfor line listings of both the major and minor isomer.
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