Binding of a Small Molecule at a Protein–Protein Interface Regulates the Chaperone Activity of Hsp70

Binding of a Small Molecule at a Protein–Protein Interface Regulates the Chaperone Activity of Hsp70–Hsp40

Published:2010-05-18 Issue:6 Volume:5 Page:611-622
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Wisén Susanne¹,Bertelsen Eric B.²,Thompson Andrea D.¹,Patury Srikanth¹,Ung Peter³,Chang Lyra¹,Evans Christopher G.¹,Walter Gladis M.¹,Wipf Peter⁴,Carlson Heather A.³,Brodsky Jeffrey L.⁵,Zuiderweg Erik R. P.²,Gestwicki Jason E.¹²³

Affiliation:

1. Department of Pathology and the Life Sciences Institute

2. Department of Biological Chemistry

3. Medicinal Chemistry, University of Michigan, Ann Arbor, Michigan

4. Department of Chemistry

5. Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/cb1000422

Reference62 articles.

1. Chaperones in control of protein disaggregation

2. Molecular Chaperones and Protein Quality Control

3. Folding of Newly Translated Proteins In Vivo: The Role of Molecular Chaperones

4. From the cradle to the grave: molecular chaperones that may choose between folding and degradation

5. Regulation of Signaling Protein Function and Trafficking by the hsp90/hsp70-Based Chaperone Machinery

Cited by 141 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. The characteristics of PtHSP40 gene family in Phaeodactylum tricornutum and its response to environmental stresses;Marine Environmental Research;2024-07

2. Catalyst-free Approach to Dihydropyrimidones Using Glycerol/Ethyl Lactate as a Recyclable and Biodegradable Promoting Medium;Letters in Organic Chemistry;2024-07

3. Plasmodium falciparum heat shock proteins as antimalarial drug targets: An update;Cell Stress and Chaperones;2024-04

4. Salidroside directly activates HSC70, revealing a new role for HSC70 in BDNF signalling and neurogenesis after cerebral ischemia;Phytotherapy Research;2024-03-15

5. J-domain proteins: From molecular mechanisms to diseases;Cell Stress and Chaperones;2024-02