Design, Structure−Activity Relationships, X-ray Crystal Structure, and Energetic Contributions of a Critical P1 Pharmacophore: 3-Chloroindole-7-yl-Based Factor Xa Inhibitors-Reference-Cited by-同舟云学术

Design, Structure−Activity Relationships, X-ray Crystal Structure, and Energetic Contributions of a Critical P1 Pharmacophore: 3-Chloroindole-7-yl-Based Factor Xa Inhibitors

Published:2008-11-11 Issue:23 Volume:51 Page:7541-7551
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Shi Yan¹,Sitkoff Doree¹,Zhang Jing¹,Klei Herbert E.¹,Kish Kevin¹,Liu Eddie C.-K.¹,Hartl Karen S.¹,Seiler Steve M.¹,Chang Ming¹,Huang Christine¹,Youssef Sonia¹,Steinbacher Thomas E.¹,Schumacher William A.¹,Grazier Nyeemah¹,Pudzianowski Andrew¹,Apedo Atsu¹,Discenza Lorell¹,Yanchunas Joseph¹,Stein Philip D.¹,Atwal Karnail S.¹

Affiliation:

1. Bristol-Myers Squibb Research & Development, P.O. Box 5400, Princeton, New Jersey 08543-5400

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm800855x

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