Development of a Structural Model for NF-κB Inhibition of Sesquiterpene Lactones Using Self-Organizing Neural Networks
Author:
Affiliation:
1. Institut für Pharmazeutische Wissenschaften, Lehrstuhl für Pharmazeutische Biologie und Biotechnologie, Universität Freiburg, 79104 Freiburg, Germany, and Computer-Chemie-Centrum, Universität Erlangen-Nürnberg, 91052 Erlangen, Germany
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm051125n
Reference41 articles.
1. SESQUITERPENE LACTONES ARE POTENT INHIBITORS OF INTERLEUKIN 8 GENE EXPRESSION IN CULTURED HUMAN RESPIRATORY EPITHELIUM
2. The Anti-inflammatory Sesquiterpene Lactone Helenalin Inhibits the Transcription Factor NF-κB by Directly Targeting p65
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