Importance of Specific Hydrogen-Bond Donor−Acceptor Interactions for the Key Carbocycle-Forming Reaction Catalyzed by 2-Deoxy-scyllo-inosose Synthase in the Biosynthesis of 2-Deoxystreptamine-Containing Aminocyclitol Antibiotics
Author:
Affiliation:
1. Department of Chemistry and Materials Science, and Department of Chemistry, Tokyo Institute of Technology, O-okayama, Meguro-ku, Tokyo 152-8551, Japan
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/jo011107n
Reference35 articles.
1. Carbon-13 as a biosynthetic tool. IV. Biosynthetic incorporation of glucosamine-1-13C and glucose-6-13C into neomycin
2. Mutational biosynthesis by idiotrophs of Micromonospora purpurea. II. Conversion of non-amino containing cyclitols to aminoglycoside antibiotics.
3. Biosynthesis of butirosins. II. Biosynthetic pathway of butirosins elucidated from cosynthesis and feeding experiments.
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