Characterization of the 5-HT7 Receptor. Determination of the Pharmacophore for 5-HT7 Receptor Agonism and CoMFA-Based Modeling of the Agonist Binding Site-Reference-Cited by-同舟云学术

Characterization of the 5-HT7 Receptor. Determination of the Pharmacophore for 5-HT7 Receptor Agonism and CoMFA-Based Modeling of the Agonist Binding Site

Published:2003-11-05 Issue:25 Volume:46 Page:5365-5374
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Vermeulen Erik S.¹,Schmidt Anne W.¹,Sprouse Jeffrey S.¹,Wikström Håkan V.¹,Grol Cor J.¹

Affiliation:

1. Department of Medicinal Chemistry, Center for Pharmacy, State University of Groningen, A. Deusinglaan 1, NL-9713 AV Groningen, The Netherlands, and Department of Neuroscience, Pfizer Global R&D, MS 8220-4178, Groton, Connecticut 06340

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm030826m

Reference42 articles.

1. 5-HT 7 receptors: current knowledge and future prospects

2. The 5-HT7 receptor: orphan found

3. Molecular cloning, characterization, and localization of a high-affinity serotonin receptor (5-HT7) activating cAMP formation.

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