ADME Evaluation in Drug Discovery. 9. Prediction of Oral Bioavailability in Humans Based on Molecular Properties and Structural Fingerprints-Reference-Cited by-同舟云学术

ADME Evaluation in Drug Discovery. 9. Prediction of Oral Bioavailability in Humans Based on Molecular Properties and Structural Fingerprints

Published:2011-05-16 Issue:3 Volume:8 Page:841-851
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Tian Sheng¹,Li Youyong¹,Wang Junmei²,Zhang Jian³,Hou Tingjun¹

Affiliation:

1. Institute of Functional Nano & Soft Materials (FUNSOM) and Jiangsu Key Laboratory for Carbon-Based Functional Materials & Devices, Soochow University, Suzhou, Jiangsu 215123, China

2. Department of Pharmacology, The University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, Texas 75390, United States

3. The Department of Pathophysiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai Jiao Tong University, School of Medicine, Shanghai 200025, China

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/mp100444g

Reference31 articles.

1. Recent Developments of In Silico Predictions of Intestinal Absorption and Oral Bioavailability

2. Structure – ADME relationship: still a long way to go?

3. Recent Development and Application of Virtual Screening in Drug Discovery: An Overview

4. Molecular Properties That Influence the Oral Bioavailability of Drug Candidates

5. A Bioavailability Score

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