Small Molecule Control of Morpholino Antisense Oligonucleotide Function through Staudinger Reduction-Reference-Cited by-同舟云学术

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Small Molecule Control of Morpholino Antisense Oligonucleotide Function through Staudinger Reduction

Published:2021-10-27 Issue:44 Volume:143 Page:18665-18671
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Darrah Kristie¹,Wesalo Joshua¹,Lukasak Bradley¹,Tsang Michael²,Chen James K.³^ORCID,Deiters Alexander¹^ORCID

Affiliation:

1. Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States

2. Department of Developmental Biology, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States

3. Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, California 94305, United States

Funder

NIH

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/jacs.1c08723

Reference59 articles.

1. The Predictive Power of Synthetic Nucleic Acid Technologies in RNA Biology

2. The chemical evolution of oligonucleotide therapies of clinical utility

3. The current state and future directions of RNAi-based therapeutics

4. Morpholino, siRNA, and S-DNA Compared: Impact of Structure and Mechanism of Action on Off-Target Effects and Sequence Specificity

5. Gene Knockdown by Morpholino-Modified Oligonucleotides in the Zebrafish (Danio rerio) Model: Applications for Developmental Toxicology

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1. Synthesis of Phosphorodiamidate Morpholino Oligonucleotides (PMOs) Using Staudinger Reduction as a Deblocking Condition and Its Usefulness for Orthogonal Conjugation in Bi- and Trifunctionalized PMOs;Synlett;2024-08-12

2. Photochemical regulatory strategies for nucleic acid function and their biomedical applications;Interdisciplinary Medicine;2024-07

3. Direct Activation of Nucleobases with Small Molecules for the Conditional Control of Antisense Function;Angewandte Chemie International Edition;2024-03-15

4. Direct Activation of Nucleobases with Small Molecules for the Conditional Control of Antisense Function;Angewandte Chemie;2024-03-15

5. A Platform Approach to Cleavable Macrocycles for the Controlled Disassembly of Mechanically Caged Molecules;Angewandte Chemie International Edition;2024-03-06

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