Unraveling the Structural Basis of Selective Inhibition of Human Cytochrome P450 3A5
Author:
Affiliation:
1. Department of Chemical Biology and Therapeutics, St. Jude Children’s Research Hospital, Memphis, Tennessee 38105, United States
2. Department of Structural Biology, St. Jude Children’s Research Hospital, Memphis, Tennessee 38105, United States
Funder
National Institute of General Medical Sciences
Publisher
American Chemical Society (ACS)
Subject
Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis
Link
https://pubs.acs.org/doi/pdf/10.1021/jacs.1c07066
Reference52 articles.
1. The Cytochrome P450 Superfamily: Biochemistry, Evolution and Drug Metabolism in Humans
2. DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
3. Predicting in vivo drug interactions from in vitro drug discovery data
4. Structural perspectives of the CYP3A family and their small molecule modulators in drug metabolism
5. Inhibition and induction of CYP enzymes in humans: an update
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