Radical-Trapping Antioxidant Activity of Copper and Nickel Bis(Thiosemicarbazone) Complexes Underlies Their Potency as Inhibitors of Ferroptotic Cell Death-Reference-Cited by-同舟云学术

Radical-Trapping Antioxidant Activity of Copper and Nickel Bis(Thiosemicarbazone) Complexes Underlies Their Potency as Inhibitors of Ferroptotic Cell Death

Published:2021-11-03 Issue:45 Volume:143 Page:19043-19057
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Zilka Omkar¹^ORCID,Poon Jia-Fei¹,Pratt Derek A.¹^ORCID

Affiliation:

1. Department of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, ON K1N 6N5, Canada

Funder

Canada Foundation for Innovation

Natural Sciences and Engineering Research Council of Canada

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/jacs.1c08254

Reference61 articles.

1. Copper(II)[2,3-Butanedionebis(N4-methylthiosemicarbazone)], a Stable Superoxide Dismutase-like Copper Complex with High Membrane Penetrability

2. Copper delivery to the CNS by CuATSM effectively treats motor neuron disease in SODG93A mice co-expressing the Copper-Chaperone-for-SOD

3. Neuroprotective effect of CuATSM on neurotoxin-induced motor neuron loss in an ALS mouse model

4. Neuroprotective effect of CuATSM in mice stroke model by ameliorating oxidative stress

5. Cu-ATSM, an Intracellular-Accessible Superoxide Dismutase (SOD)-Like Copper Complex: Evaluation in an Ischemia-Reperfusion Injury Model.

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