N+/Si Replacement as a Tool for Probing the Pharmacophore of Allosteric Modulators of Muscarinic M2 Receptors: Synthesis, Allosteric Potency, and Positive Cooperativity of Silicon-Based W84 Derivatives-Reference-Cited by-同舟云学术

N+/Si Replacement as a Tool for Probing the Pharmacophore of Allosteric Modulators of Muscarinic M2 Receptors: Synthesis, Allosteric Potency, and Positive Cooperativity of Silicon-Based W84 Derivatives

Published:2002-01-25 Issue:5 Volume:21 Page:803-811
ISSN:0276-7333
Container-title:Organometallics
language:en
Short-container-title:Organometallics

Author:

Daiss Jürgen O.¹,Duda-Johner Seraina¹,Burschka Christian¹,Holzgrabe Ulrike¹,Mohr Klaus¹,Tacke Reinhold¹

Affiliation:

1. Institut für Anorganische Chemie, Universität Würzburg, Am Hubland, D-97074 Würzburg, Germany, Institut für Pharmazie und Lebensmittelchemie, Universität Würzburg, Am Hubland, D-97074 Würzburg, Germany, and Pharmakologie und Toxikologie, Pharmazeutisches Institut, Universität Bonn, An der Immenburg 4, D-53121 Bonn, Germany

Publisher

American Chemical Society (ACS)

Subject

Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/om010847j

Reference28 articles.

1. Allosteric regulation of cloned m1–m5 muscarinic receptor subtypes

2. Allosteric modulators of ligand binding to muscarinic acetylcholine receptors

3. M2 Receptor Binding of the Selective Antagonist AF-DX 384: Possible Involvement of the Common Allosteric Site

Cited by 25 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. The role of silicon in drug discovery: a review;RSC Medicinal Chemistry;2024

2. Pt(0)-Catalysed synthesis of new bifunctional silanes;Dalton Transactions;2020

3. The effect of organosilicon modifier structure on the efficiency of the polybutadiene hydrosilylation process;Catalysis Science & Technology;2020

4. Methods for the Preparation of Modified Polyorganosiloxanes (A Review);Oriental Journal of Chemistry;2018-04-25

5. Quest for Novel Chemical Entities through Incorporation of Silicon in Drug Scaffolds;Journal of Medicinal Chemistry;2017-10-17