Synthesis and Biological Evaluation of 2‘,3‘-Didehydro-2‘,3‘-dideoxy-5- fluorocytidine (D4FC) Analogues: Discovery of Carbocyclic Nucleoside Triphosphates with Potent Inhibitory Activity against HIV-1 Reverse Transcriptase-Reference-Cited by-同舟云学术

Synthesis and Biological Evaluation of 2‘,3‘-Didehydro-2‘,3‘-dideoxy-5- fluorocytidine (D4FC) Analogues: Discovery of Carbocyclic Nucleoside Triphosphates with Potent Inhibitory Activity against HIV-1 Reverse Transcriptase

Published:1999-02-20 Issue:5 Volume:42 Page:859-867
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Shi Junxing¹,McAtee J. Jeffrey¹,Schlueter Wirtz Susan¹,Tharnish Phillip¹,Juodawlkis Amy¹,Liotta Dennis C.¹,Schinazi Raymond F.¹

Affiliation:

1. Departments of Pediatrics and Chemistry, Emory University, Atlanta, Georgia 30322, and The Georgia Veterans Affairs Research Center for AIDS and HIV Infections, 1670 Clairmont Road, Decatur, Georgia 30033

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm980510s

Reference22 articles.

1. 1-(2,3-Dideoxy-.beta.-D-glycero-pent-2-enofuranosyl)thymine. A highly potent and selective anti-HIV agent

2. Insights Into HIV Chemotherapy*

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