Attrition-Enhanced Deracemization in the Synthesis of Clopidogrel - A Practical Application of a New Discovery-Reference-Cited by-同舟云学术

Attrition-Enhanced Deracemization in the Synthesis of Clopidogrel - A Practical Application of a New Discovery

Published:2009-11-04 Issue:6 Volume:13 Page:1195-1198
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

van der Meijden Maarten W.¹,Leeman Michel¹,Gelens Edith¹,Noorduin Wim L.¹,Meekes Hugo¹,van Enckevort Willem J. P.¹,Kaptein Bernard¹,Vlieg Elias¹,Kellogg Richard M.¹

Affiliation:

1. Syncom BV, Kadijk 3, 9737 AT Groningen, The Netherlands, IMM Solid State Chemistry, Radboud University Nijmegen Heyendaalseweg 135, 6525 AJ Nijmegen, The Netherland, and DSM Pharmaceutical Products, Innovative Synthesis and Catalysis, PO Box 18, 6160 MD Geleen, The Netherlands

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/op900243c

Reference29 articles.

1. For NaClO3, which forms a solid conglomerate, from a saturated solution in contact with the solid:

2. Chiral Symmetry Breaking During Crystallization: Complete Chiral Purity Induced by Nonlinear Autocatalysis and Recycling

3. Chiral Symmetry Breaking in Sodium Chlorate Crystallization

4. Emergence of a Single Solid Chiral State from a Nearly Racemic Amino Acid Derivative

5. Complete asymmetric amplification of ethylenediammonium sulfate using an abrasion/grinding technique

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