Allele-Selective Inhibition of Mutant Huntingtin Expression with Antisense Oligonucleotides Targeting the Expanded CAG Repeat-Reference-Cited by-同舟云学术

Allele-Selective Inhibition of Mutant Huntingtin Expression with Antisense Oligonucleotides Targeting the Expanded CAG Repeat

Published:2010-11-08 Issue:47 Volume:49 Page:10166-10178
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Gagnon Keith T.¹,Pendergraff Hannah M.¹,Deleavey Glen F.²,Swayze Eric E.³,Potier Pierre⁴,Randolph John⁵,Roesch Eric B.⁵,Chattopadhyaya Jyoti⁶,Damha Masad J.²,Bennett C. Frank³,Montaillier Christophe⁴,Lemaitre Marc⁵,Corey David R.¹

Affiliation:

1. Departments of Pharmacology and Biochemistry, UT Southwestern Medical Center, ND8.136B, Dallas, Texas 75390-9041, United States

2. Department of Chemistry, McGill University, Montreal, Quebec H3A 2K6, Canada

3. Isis Pharmaceuticals, 1896 Rutherford Road, Carlsbad, California 92008, United States

4. SIGMA Custom Products, Genopole Campus 1, 5 Rue Desbruères, 91030 Evry Cedex, France

5. Glen Research Corporation, 22825 Davis Drive, Sterling, Virginia 20164, United States

6. Department of Bioorganic Chemistry, Uppsala University, Biomedical Center, Box 581, S-751 23 Uppsala, Sweden

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/bi101208k

Reference77 articles.

1. Trinucleotide Repeat Disorders

2. Huntington's disease

3. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes

4. Molecular Biology of Huntington's Disease (HD) and HD-Like Disorders

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