Antischistosomal Properties of Sclareol and Its Heck-Coupled Derivatives: Design, Synthesis, Biological Evaluation, and Untargeted Metabolomics-Reference-Cited by-同舟云学术

Antischistosomal Properties of Sclareol and Its Heck-Coupled Derivatives: Design, Synthesis, Biological Evaluation, and Untargeted Metabolomics

Published:2019-05-13 Issue:7 Volume:5 Page:1188-1199
ISSN:2373-8227
Container-title:ACS Infectious Diseases
language:en
Short-container-title:ACS Infect. Dis.

Author:

Crusco Alessandra¹²,Whiteland Helen¹,Baptista Rafael¹,Forde-Thomas Josephine E.¹,Beckmann Manfred¹,Mur Luis A. J.¹,Nash Robert J.³,Westwell Andrew D.²,Hoffmann Karl F.¹^ORCID

Affiliation:

1. Institute of Biological, Environmental and Rural Sciences (IBERS), Aberystwyth University, Penglais Campus, Aberystwyth SY23 3DA, United Kingdom

2. School of Pharmacy and Pharmaceutical Sciences, Cardiff University, Cardiff CF10 3NB, United Kingdom

3. PhytoQuest Limited, Plas Gogerddan, Aberystwyth, Ceredigion SY23 3EB, Wales, United Kingdom

Funder

Biotechnology and Biological Sciences Research Council

Life Sciences Research Network Wales

Publisher

American Chemical Society (ACS)

Subject

Infectious Diseases

Link

http://pubs.acs.org/doi/pdf/10.1021/acsinfecdis.9b00034

Reference56 articles.

1. Discovery and functional characterization of two diterpene synthases for sclareol biosynthesis in Salvia sclarea(L.) and their relevance for perfume manufacture

2. A toxicologic and dermatologic assessment of cyclic and non-cyclic terpene alcohols when used as fragrance ingredients

3. Mechanisms of resistance to self-produced toxic secondary metabolites in plants

4. Effect of 13-epi-Sclareol on the Bacterial Respiratory Chain

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