Design of Next Generation Polymyxins with Lower Toxicity: The Discovery of SPR206-Reference-Cited by-同舟云学术

Design of Next Generation Polymyxins with Lower Toxicity: The Discovery of SPR206

Published:2019-09-17 Issue:10 Volume:5 Page:1645-1656
ISSN:2373-8227
Container-title:ACS Infectious Diseases
language:en
Short-container-title:ACS Infect. Dis.

Author:

Brown Pamela¹²^ORCID,Abbott Elizabeth¹,Abdulle Omar¹,Boakes Steven¹,Coleman Scott²,Divall Naomi¹,Duperchy Esther¹,Moss Stephen³,Rivers Dean¹,Simonovic Mona¹,Singh Jaspal¹,Stanway Steven³,Wilson Antoinette³,Dawson Michael J.¹²

Affiliation:

1. Cantab Anti-Infectives Ltd., BioPark, Broadwater Road, Welwyn Garden City, Hertfordshire AL7 3AX, United Kingdom

2. Spero Therapeutics Inc., 675 Massachusetts Avenue, 14th Floor, Cambridge, Massachusetts 02139, United States

3. Eurofins Selcia Drug Discovery, U.K., Fyfield Business & Research Park, Fyfield Road, Ongar, Essex CM5 0GS, United Kingdom

Funder

National Institute of Allergy and Infectious Diseases

Innovate UK

Publisher

American Chemical Society (ACS)

Subject

Infectious Diseases

Link

https://pubs.acs.org/doi/pdf/10.1021/acsinfecdis.9b00217

Reference38 articles.

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2. Re-estimating annual deaths due to multidrug-resistant organism infections

3. The impact of polymyxin B dosage on in-hospital mortality of patients treated with this antibiotic

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