Calcium Ions Directly Interact with the Ebola Virus Fusion Peptide To Promote Structure–Function Changes That Enhance Infection

Author:

Nathan Lakshmi1,Lai Alex L.2,Millet Jean Kaoru3ORCID,Straus Marco R.3,Freed Jack H.2ORCID,Whittaker Gary R.3,Daniel Susan1ORCID

Affiliation:

1. Robert Frederick Smith School of Chemical and Biomolecular Engineering, Cornell University, 120 Olin Hall, Ithaca, New York 14853, United States

2. Baker Laboratory, Department of Chemistry and Chemical Biology, Cornell University, Ithaca, New York 14853, United States

3. Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York 14853, United States

Funder

Division of Molecular and Cellular Biosciences

Division of Graduate Education

National Institutes of Health

Publisher

American Chemical Society (ACS)

Subject

Infectious Diseases

Reference52 articles.

1. Ebola haemorrhagic fever

2. Centers for Disease Control and Prevention. (accessed May 24, 2018) Years of Ebola Virus Disease Outbreaks, https://www.cdc.gov/vhf/ebola/history/chronology.html.

3. World Health Organization. Ebola virus disease: Fact sheet, http://www.who.int/mediacentre/factsheets/fs103/en/.

4. A Recombinant Vesicular Stomatitis Virus Ebola Vaccine

5. Chimpanzee Adenovirus Vector Ebola Vaccine

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