Macrofilaricidal Benzimidazole–Benzoxaborole Hybrids as an Approach to the Treatment of River Blindness: Part 1. Amide Linked Analogs

Author:

Akama Tsutomu1,Freund Yvonne R.1,Berry Pamela W.1,Carter David S.1,Easom Eric E.1,Jarnagin Kurt1,Lunde Christopher S.1,Plattner Jacob J.1,Rock Fernando1,Stefanakis Rianna1,Fischer Chelsea2,Bulman Christina A.2,Lim Kee Chong2,Suzuki Brian M.3,Tricoche Nancy4,Mansour Abdelmoneim5,DiCosty Utami5,McCall Scott5,Carson Ben5,McCall John W.5,McKerrow James3,Hübner Marc P.6,Specht Sabine67,Hoerauf Achim6,Lustigman Sara4,Sakanari Judy A.2ORCID,Jacobs Robert T.1ORCID

Affiliation:

1. Anacor Pharmaceuticals, Inc., 1020 E. Meadow Circle, Palo Alto, California 94303, United States

2. Department of Pharmaceutical Chemistry, University of California San Francisco, 1700 4th Street, San Francisco, California 94158, United States

3. Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, 9500 Gilman Drive, La Jolla, California 92093-0657, United States

4. Lindsley F. Kimball Research Institute, New York Blood Center, 310 E. 67th Street, New York, New York 10065, United States

5. TRS Laboratories, Inc., 295 Research Drive, Athens, Georgia 30605, United States

6. Institute for Medical Microbiology, Immunology and Parasitology, University Hospital Bonn, Sigmund Freud Strasse 25, 53127 Bonn, Germany

7. Drugs for Neglected Diseases Initiative, 15 Chemin Louis-Dunant, 1202 Geneva, Switzerland

Funder

Bill and Melinda Gates Foundation

Publisher

American Chemical Society (ACS)

Subject

Infectious Diseases

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