Exploring the SAR of the β-Ketoacyl-ACP Synthase Inhibitor GSK3011724A and Optimization around a Genotoxic Metabolite-Reference-Cited by-同舟云学术

Exploring the SAR of the β-Ketoacyl-ACP Synthase Inhibitor GSK3011724A and Optimization around a Genotoxic Metabolite

Published:2020-03-20 Issue:5 Volume:6 Page:1098-1109
ISSN:2373-8227
Container-title:ACS Infectious Diseases
language:en
Short-container-title:ACS Infect. Dis.

Author:

Cunningham Fraser¹,Esquivias Jorge¹,Fernández-Menéndez Raquel¹,Pérez Arancha¹,Guardia Ana¹,Escribano Jaime¹,Rivero Cristina¹,Vimal Mythily²,Cacho Mónica¹^ORCID,de Dios-Antón Paco¹,Martínez-Martínez María Santos¹,Jiménez Elena¹,Huertas Valentín Leticia¹,Rebollo-López María José¹,López-Román Eva María¹,Sousa-Morcuende Verónica¹,Rullas Joaquín¹,Neu Margaret²,Chung Chun-wa²,Bates Robert H.¹^ORCID

Affiliation:

1. Global Health R&D, GlaxoSmithKline, Severo Ochoa 2, Tres Cantos, 28760 Madrid, Spain

2. GlaxoSmithKline, Gunnels Wood Road, Stevenage SG1 2NY, U.K.

Funder

TB Alliance

Publisher

American Chemical Society (ACS)

Subject

Infectious Diseases

Link

https://pubs.acs.org/doi/pdf/10.1021/acsinfecdis.9b00493

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