Discovery, Synthesis, and Optimization of 1,2,4-Triazolyl Pyridines Targeting Mycobacterium tuberculosis

Author:

Berida Tomayo1ORCID,McKee Samuel R.2,Chatterjee Shamba1ORCID,Manning Destinee L.1ORCID,Li Wei3,Pandey Pankaj4ORCID,Tripathi Siddharth Kaushal4,Mreyoud Yassin2,Smirnov Asya2,Doerksen Robert J.1ORCID,Jackson Mary3ORCID,Ducho Christian5ORCID,Stallings Christina L.2,Roy Sudeshna1ORCID

Affiliation:

1. Department of BioMolecular Sciences, University of Mississippi, University, Mississippi 38677, United States

2. Department of Molecular Microbiology, Center for Women’s Infectious Disease Research, Washington University School of Medicine, St. Louis, Missouri 63110, United States

3. Mycobacteria Research Laboratories, Department of Microbiology, Immunology, and Pathology, Colorado State University, 1682 Campus Delivery, Fort Collins, Colorado 80523, United States

4. National Center for Natural Products Research, University of Mississippi, University, Mississippi 38677, United States

5. Department of Pharmacy, Pharmaceutical and Medicinal Chemistry, Saarland University, Saarbrücken 66123, Germany

Funder

National Cancer Institute

National Center for Research Resources

Agricultural Research Service

National Institute of Allergy and Infectious Diseases

University of Mississippi

Burroughs Wellcome Fund

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

Infectious Diseases

Reference59 articles.

1. World Health Organization, (WHO). Global Tuberculosis Report 2021; Geneva (Switzerland), 2021.

2. Multidrug-Resistant Tuberculosis and Extensively Drug-Resistant Tuberculosis

3. Tuberculosis

4. Evolution of Drug-Resistant Mycobacterium tuberculosis Strains and Their Adaptation to the Human Lung Environment

5. World Health Organization, (WHO). Global Tuberculosis Report 2020; Geneva (Switzerland), 2020.

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