A Pyridyl-Furan Series Developed from the Open Global Health Library Block Red Blood Cell Invasion and Protein Trafficking in Plasmodium falciparum through Potential Inhibition of the Parasite’s PI4KIIIB Enzyme

Author:

Ling Dawson B.12,Nguyen William34,Looker Oliver1ORCID,Razook Zahra15,McCann Kirsty15,Barry Alyssa E.15,Scheurer Christian67,Wittlin Sergio67ORCID,Famodimu Mufuliat Toyin8,Delves Michael J8ORCID,Bullen Hayley E.12,Crabb Brendan S.129,Sleebs Brad E.34ORCID,Gilson Paul R.12ORCID

Affiliation:

1. Burnet Institute, Melbourne, Victoria3004, Australia

2. Department of Microbiology and Immunology, University of Melbourne, Melbourne, Victoria3010, Australia

3. The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria3052, Australia

4. Department of Medical Biology, The University of Melbourne, Parkville, Victoria3010, Australia

5. School of Medicine and Institute for Mental and Physical Health and Clinical Translation, Deakin University, Waurn Ponds, Victoria3216, Australia

6. Swiss Tropical and Public Health Institute, Allschwil, 4123Switzerland

7. University of Basel, Basel, 4001Switzerland

8. Department of Infection Biology, Faculty of Infectious Diseases, London School of Hygiene and Tropical Medicine, Kepel Street, London, WC1E 7HT, U.K.

9. Department of Immunology and Pathology, Monash University, Melbourne, Victoria3800, Australia

Funder

Burnet Institute

National Health and Medical Research Council

Publisher

American Chemical Society (ACS)

Subject

Infectious Diseases

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