Antifungal and Antiparasitic Activities of Metallocene-Containing Fluconazole Derivatives

Author:

Lin Yan1,Scalese Gonzalo2,Bulman Christina A.3,Vinck Robin1,Blacque Olivier4,Paulino Margot5,Ballesteros-Casallas Andres5,Pérez Díaz Leticia6,Salinas Gustavo78,Mitreva Makedonka9,Weil Tobias10,Cariou Kevin1,Sakanari Judy A.3ORCID,Gambino Dinorah2ORCID,Gasser Gilles1ORCID

Affiliation:

1. Chimie ParisTech, PSL University, CNRS, Institute of Chemistry for Life and Health Sciences, Laboratory for Inorganic Chemical Biology, 75005 Paris, France

2. Área Química Inorgánica, Facultad de Química, Universidad de la República, 11800 Montevideo, Uruguay

3. Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, California 94158, United States

4. Department of Chemistry, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland

5. Área Bioinformática, Departamento DETEMA, Facultad de Química, Universidad de la República, 11600 Montevideo, Uruguay

6. Sección Genómica Funcional, Facultad de Ciencias, Universidad de la República, 11400 Montevideo, Uruguay

7. Worm Biology Lab, Institut Pasteur de Montevideo, 11400 Montevideo, Uruguay

8. Departamento de Biociencias, Facultad de Química, Universidad de la República, 11800 Montevideo, Uruguay

9. Department of Medicine, Washington University School of Medicine, St. Louis, Missouri 63108, United States

10. Research and Innovation Centre, Fondazione Edmund Mach, Via E. Mach 1, 38010 San Michele all’Adige, Italy

Funder

Agence Nationale de la Recherche

Schweizerischer Nationalfonds zur F?rderung der Wissenschaftlichen Forschung

Provincia Autonoma di Trento

Minist?re de l'Enseignement Sup?rieur et de la Recherche Scientifique

Universidad de la Rep?blica Uruguay

Universit? de Recherche Paris Sciences et Lettres

Minist?re de l'Europe et des Affaires ?trang?res

H2020 European Research Council

Fondo para la Convergencia Estructural del MERCOSUR

Quantitative Biosciences Institute, University of California San Francisco

Publisher

American Chemical Society (ACS)

Reference63 articles.

1. Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017

2. Global, regional, and national age–sex specific all-cause and cause-specific mortality for 240 causes of death, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013

3. Chagas disease (also known as American trypanosomiasis); https://www.who.int/news-room/fact-sheets/detail/chagas-disease-(american-trypanosomiasis) (accessed Jan 26, 2024)

4. American Trypanosomiasis; https://www.cdc.gov/dpdx/trypanosomiasisamerican/index.html (accessed Jan 26, 2024)

5. Chagas’ Disease

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