Isofagomine Inhibits Multiple TcdB Variants and Protects Mice from <i>Clostridioides difficile</i>-Induced Mortality-Reference-Cited by-同舟云学术

Isofagomine Inhibits Multiple TcdB Variants and Protects Mice from Clostridioides difficile-Induced Mortality

Published:2024-02-09 Issue:3 Volume:10 Page:928-937
ISSN:2373-8227
Container-title:ACS Infectious Diseases
language:en
Short-container-title:ACS Infect. Dis.

Author:

Paparella Ashleigh S.¹,Brew Isabella¹,Hong Huynh A.²,Ferriera William²,Cutting Simon²,Lamiable-Oulaidi Farah³,Popadynec Michael³,Tyler Peter C.³^ORCID,Schramm Vern L.¹^ORCID

Affiliation:

1. Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York 10461, United States

2. SporeGen Ltd., The London BioScience Innovation Centre, London NW1 0NH, U.K.

3. The Ferrier Research Institute, Victoria University of Wellington, Lower Hutt 5010, New Zealand

Funder

National Institute of Allergy and Infectious Diseases

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acsinfecdis.3c00507

Reference30 articles.

1. Centers for Disease Control and Prevention. Antibiotic Resistance Threats in the United States, 2019.

2. Burden of Clostridium difficile on the Healthcare System

3. Clostridium difficile infection

4. Guidelines for Diagnosis, Treatment, and Prevention of Clostridium difficile Infections

5. Clinical Practice Guidelines for Clostridium difficile Infection in Adults: 2010 Update by the Society for Healthcare Epidemiology of America (SHEA) and the Infectious Diseases Society of America (IDSA)

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