Potency of CRISPR-Cas Antifungals Is Enhanced by Cotargeting DNA Repair and Growth Regulatory Machinery at the Genetic Level
Author:
Affiliation:
1. Department of Chemical and Biomolecular Engineering, University of Tennessee, Knoxville, Tennessee 37996, United States
Funder
Defense Advanced Research Projects Agency
Publisher
American Chemical Society (ACS)
Subject
Infectious Diseases
Link
https://pubs.acs.org/doi/pdf/10.1021/acsinfecdis.3c00342
Reference32 articles.
1. Antifungal Therapy: New Advances in the Understanding and Treatment of Mycosis
2. New CRISPR Mutagenesis Strategies Reveal Variation in Repair Mechanisms among Fungi
3. Hidden Killers: Human Fungal Infections
4. Global and Multi-National Prevalence of Fungal Diseases—Estimate Precision
5. Climate change and the emergence of fungal pathogens
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1. Molecular Detection of Phytophthora cinnamomi by RPA-CRISPR/Cas12a-Mediated Isothermal Amplification;Forests;2024-04-28
2. CRISPR-GRIT: Guide-RNAs with Integrated Repair Templates Enable Precise Multiplexed Genome Editing in the Diploid Fungal PathogenCandida albicans;2023-11-28
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