Combining Gallium Protoporphyrin and Gallium Nitrate Enhances In Vitro and In Vivo Efficacy against Pseudomonas aeruginosa: Role of Inhibition of Bacterial Antioxidant Enzymes and Resultant Increase in Cytotoxic Reactive Oxygen Species-Reference-Cited by-同舟云学术

Combining Gallium Protoporphyrin and Gallium Nitrate Enhances In Vitro and In Vivo Efficacy against Pseudomonas aeruginosa: Role of Inhibition of Bacterial Antioxidant Enzymes and Resultant Increase in Cytotoxic Reactive Oxygen Species

Published:2022-09-01 Issue:10 Volume:8 Page:2096-2105
ISSN:2373-8227
Container-title:ACS Infectious Diseases
language:en
Short-container-title:ACS Infect. Dis.

Author:

Scott Zachary W.¹,Choi Seoung-ryoung¹^ORCID,Talmon Geoffrey A.¹,Britigan Bradley E.¹²³,Narayanasamy Prabagaran¹^ORCID

Affiliation:

1. Department of Pathology and Microbiology, College of Medicine, University of Nebraska Medical Center, Omaha, Nebraska 68198, United States

2. Department of Internal Medicine, College of Medicine, University of Nebraska Medical Center, Omaha, Nebraska 68198, United States

3. Department of Internal Medicine and Research Service, Veterans Affairs Medical Center-Nebraska Western Iowa, Omaha, Nebraska 68105, United States

Funder

Nebraska Research Initiative

Publisher

American Chemical Society (ACS)

Subject

Infectious Diseases

Link

https://pubs.acs.org/doi/pdf/10.1021/acsinfecdis.2c00196

Reference26 articles.

1. Organization, W. H. Antimicrobial Resistance Global Reporton Surveillance for Organization, W. H. June 2014 2014.

2. Characterization of gallium resistance induced in a Pseudomonas aeruginosa cystic fibrosis isolate

3. Iron Regulatory Proteins Mediate Host Resistance to Salmonella Infection

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