A Target Engagement Assay to Assess Uptake, Potency, and Retention of Antibiotics in Living Bacteria-Reference-Cited by-同舟云学术

A Target Engagement Assay to Assess Uptake, Potency, and Retention of Antibiotics in Living Bacteria

Published:2022-07-11 Issue:8 Volume:8 Page:1449-1467
ISSN:2373-8227
Container-title:ACS Infectious Diseases
language:en
Short-container-title:ACS Infect. Dis.

Author:

Fanti Rebeka C.¹²,Vasconcelos Stanley N. S.¹,Catta-Preta Carolina M. C.¹,Sullivan Jaryd R.³⁴⁵,Riboldi Gustavo P.¹,dos Reis Caio V.¹,Ramos Priscila Z.¹,Edwards Aled M.⁶^ORCID,Behr Marcel A.³⁴⁵⁷,Couñago Rafael M.¹²^ORCID

Affiliation:

1. Centro de Química Medicinal (CQMED), Centro de Biologia Molecular e Engenharia Genética (CBMEG), Universidade Estadual de Campinas (UNICAMP), Campinas 13083-886, Brazil

2. Post-Graduate Program in Genetics and Molecular Biology (PGBM), UNICAMP, Campinas 13083-970, Brazil

3. Department of Microbiology & Immunology, McGill University, Montréal H3A 2B4, Canada

4. Infectious Diseases and Immunity in Global Health Program, Research Institute of the McGill University Health Centre, Montréal H4A 3J1, Canada

5. McGill International TB Centre, Montréal H4A 3S5, Canada

6. Structural Genomics Consortium, 101 College Street, Toronto M5G 1L7, Canada

7. Department of Medicine, McGill University Health Centre, Montréal H4A 3J1, Canada

Funder

Cystic Fibrosis Canada

Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico

Funda??o de Amparo ? Pesquisa do Estado de S?o Paulo

Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior

Structural Genomics Consortium

Publisher

American Chemical Society (ACS)

Subject

Infectious Diseases

Link

https://pubs.acs.org/doi/pdf/10.1021/acsinfecdis.2c00073

Reference74 articles.

1. Permeability Barrier of Gram-Negative Cell Envelopes and Approaches To Bypass It

2. Molecular Basis of Bacterial Outer Membrane Permeability Revisited

3. Porins and small-molecule translocation across the outer membrane of Gram-negative bacteria

4. The importance of efflux pumps in bacterial antibiotic resistance

5. The Role of Antibiotic-Target-Modifying and Antibiotic-Modifying Enzymes in Mycobacterium abscessus Drug Resistance

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