Synthesis and Biological Evaluation of Novel 2-(Benzofuran-2-yl)-chromone Derivatives for In Vivo Imaging of Prion Deposits in the Brain

Author:

Nakaie Mari1,Katayama Fumihiro1,Nakagaki Takehiro2,Yoshida Sakura1,Kawasaki Masao1,Nishi Kodai3,Ogawa Kazuma45ORCID,Toriba Akira1,Nishida Noriyuki2,Nakayama Morio1,Fuchigami Takeshi6ORCID

Affiliation:

1. Department of Hygienic Chemistry, Graduate School of Biomedical Sciences, Nagasaki University, 1-14 Bunkyo-machi, Nagasaki 852-8521, Japan

2. Department of Molecular Microbiology and Immunology, Graduate School of Biomedical Sciences, Nagasaki University, 1-12-4 Sakamoto, Nagasaki 852-8523, Japan

3. Department of Radioisotope Medicine, Atomic Bomb Disease Institute, Nagasaki University, 1-12-4 Sakamoto, Nagasaki 852-8523, Japan

4. Laboratory of Clinical Analytical Sciences, Graduate School of Medical Sciences, Kanazawa University, Kakuma-machi, Kanazawa, Ishikawa 920-1192, Japan

5. Institute for Frontier Science Initiative, Kanazawa University, Kakuma-machi, Kanazawa, Ishikawa 920-1192, Japan

6. Laboratory of Clinical Analytical Sciences, Graduate School, Division of Pharmaceutical Sciences, Kanazawa University, Kakuma-machi, Kanazawa, Ishikawa 920-1192, Japan

Funder

GlaxoSmithKline Japan

Takeda Science Foundation

Japan Society for the Promotion of Science

Publisher

American Chemical Society (ACS)

Subject

Infectious Diseases

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