High-Throughput Assay for Identifying Diverse Antagonists of the Binding Interaction between the ACE2 Receptor and the Dynamic Spike Proteins of SARS-CoV-2-Reference-Cited by-同舟云学术

High-Throughput Assay for Identifying Diverse Antagonists of the Binding Interaction between the ACE2 Receptor and the Dynamic Spike Proteins of SARS-CoV-2

Published:2022-10-31 Issue:11 Volume:8 Page:2259-2270
ISSN:2373-8227
Container-title:ACS Infectious Diseases
language:en
Short-container-title:ACS Infect. Dis.

Author:

Sammons Rachel M.¹^ORCID,Bohanon Amanda L.²^ORCID,Kowtha Anvith³,Dejong Audrey³,Cho Eun Jeong¹,Kaoud Tamer S.¹³^ORCID,Dalby Kevin N.¹³^ORCID

Affiliation:

1. Targeted Therapeutic Drug Discovery and Development Program, The University of Texas at Austin, Austin, Texas 78712, United States

2. Department of Molecular Biosciences, The University of Texas at Austin, Austin, Texas 78712, United States

3. Division of Chemical Biology and Medicinal Chemistry, The University of Texas at Austin, Austin, Texas 78712, United States

Funder

Welch Foundation

Publisher

American Chemical Society (ACS)

Subject

Infectious Diseases

Link

https://pubs.acs.org/doi/pdf/10.1021/acsinfecdis.2c00297

Reference39 articles.

1. FDA authorizes first single-shot COVID-19 vaccine

2. Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein

3. SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

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