Intranasal Administration of Bedaquiline-Loaded Fucosylated Liposomes Provides Anti-Tubercular Activity while Reducing the Potential for Systemic Side Effects-Reference-Cited by-同舟云学术

Intranasal Administration of Bedaquiline-Loaded Fucosylated Liposomes Provides Anti-Tubercular Activity while Reducing the Potential for Systemic Side Effects

Published:2024-08-13 Issue:9 Volume:10 Page:3222-3232
ISSN:2373-8227
Container-title:ACS Infectious Diseases
language:en
Short-container-title:ACS Infect. Dis.

Author:

Marwitz Franziska¹²,Hädrich Gabriela³⁴,Redinger Natalja⁵,Besecke Karen F. W.⁶⁷⁸,Li Feng³⁴⁹,Aboutara Nadine¹²,Thomsen Simone¹,Cohrs Michaela⁴¹⁰^ORCID,Neumann Paul Robert⁴,Lucas Henrike⁴,Kollan Julia⁴,Hozsa Constantin⁶⁷,Gieseler Robert K.⁶¹¹,Schwudke Dominik¹²¹²¹³^ORCID,Furch Marcus⁶¹⁴,Schaible Ulrich²⁵,Dailey Lea Ann³^ORCID

Affiliation:

1. Bioanalytical Chemistry, Research Center Borstel, Leibniz Lung Center, Parkallee 1−40, Borstel 23845, Germany

2. German Center for Infection Research, Thematic Translational Unit Tuberculosis, Borstel 23845, Germany

3. Department of Pharmaceutical Sciences, University of Vienna, Josef-Holaubek-Platz 2 ,Vienna 1090, Austria

4. Institute of Pharmacy, Martin-Luther-Universität Halle-Wittenberg, Kurt-Mothes-Str. 3, Halle/Saale 06120, Germany

5. Cellular Microbiology, Research Center Borstel, Leibniz Lung Center, Parkallee 1−40 ,Borstel 23845, Germany

6. Rodos Biotarget GmbH, Feodor-Lynen-Straße 31, Hannover 30625, Germany

7. Siegfried Hameln GmbH, Langes Feld 13 ,Hameln 31789, Germany

8. Cardior Pharmaceuticals GmbH, Hollerithallee 20 ,Hannover 30419, Germany

9. Vienna Doctoral School of Pharmaceutical, Nutritional and Sport Sciences (PhaNuSpo), University of Vienna, Josef-Holaubek-Platz 2 ,Vienna 1090, Austria

10. General Biochemistry and Physical Pharmacy, Faculty of Pharmaceutical Sciences, Ghent University, Ottergemsesteenweg 460 ,Ghent 9000, Belgium

11. Department of Medicine, University Hospital, Knappschaftskrankenhaus Bochum, Ruhr University Bochum, In der Schornau 23−25 ,Bochum 44892, Germany

12. German Center for Lung Research (DZL), Airway Research Center North (ARCN), Research Center Borstel, Leibniz Lung Center, Borstel 23845, Germany

13. Kiel Nano, Surface and Interface Sciences (KiNSIS), Kiel University, Kiel 24118, Germany

14. Certmedica International GmbH, Magnolienweg 17 ,Aschaffenburg 63741, Germany

Funder

Bundesministerium f?r Bildung und Forschung

China Scholarship Council

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acsinfecdis.4c00192

Reference38 articles.

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2. Bedaquiline and multidrug-resistant tuberculosis: a systematic and critical analysis of the evidence

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5. https://pubchem.ncbi.nlm.nih.gov/compound/Bedaquiline.